Eric Daar, MD; Joseph Eron, MD; and Colleen Kelley, MD, remark on therapies that are in the pipeline for the prevention of HIV infection.

Joseph Eron, MD: Colleen, what about new interventions for prevention in the antiviral space? What are we looking at?

Colleen Kelley, MD: I think I mentioned this before, but it’s such an exciting time. There are so many other options that are in the pipeline for prevention. Right now, we have 1 FDA-approved option for PrEP [pre-exposure prophylaxis]—Truvada. But, at some point, we may have a suitcase. People can pick and choose what’s going to work best for them—for their situation and lifestyle. That’s where we need to get, as a field, with HIV prevention.

There are 3 things to mention. One is a dapivirine ring, which is an NNRTI [non-nucleoside reverse transcriptase inhibitor]-formulated ring that women insert into the vagina every month. They’re looking at longer formulations of that, as well, to prevent HIV infection. This was shown to be efficacious in women in Africa. Although it may not have been as efficacious as we would have liked, this is one of the first controlled prevention interventions for women where there’s no condom negotiation. There are no power struggles. A woman can control her HIV prevention as desired. Read more via MD